Description

Propionylglycine, Di-Tms is a high-purity, silylated derivative of propionylglycine, a key intermediate in organic synthesis and analytical chemistry. This compound is specifically designed for applications requiring enhanced volatility and stability for gas chromatography (GC) and mass spectrometry (MS) analysis. It is an essential reagent for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced material sectors who require precise and reliable analytical standards or protected synthetic intermediates.

Application

• Derivatization Agent for GC/MS Analysis: Used to increase the volatility and thermal stability of organic acids and amino acids for accurate quantification in complex matrices.
• Pharmaceutical Intermediate: Serves as a protected building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and peptide analogs.
• Metabolomics Research: A critical standard or reagent in the profiling and identification of metabolic biomarkers in biological samples.
• Proteomics and Biochemical Research: Employed in the study of protein modifications and enzymatic pathways involving short-chain acyl glycines.
• Quality Control Reference Standard: Used as an analytical reference material to ensure the purity and identity of related compounds in production batches.
• Material Science Synthesis: Acts as a precursor or modifying agent in the development of specialized silicon-containing polymers or coatings.

Basic Information

Product Name	Propionylglycine, Di-Tms
CAS No.	55557-16-9
Molecular Formula	C11H25NO3Si2
Molecular Weight	275.50 g/mol
Synonyms	N-Propionylglycine bis(trimethylsilyl) ester; Bis(trimethylsilyl) N-propionylglycinate; Propionylglycine Di(trimethylsilyl) Ether; 2-[(Trimethylsilyl)oxy]-N-[(trimethylsilyl)oxy]carbonyl]propanamide; TMS derivative of Propionylglycine; Di-TMS Propionylglycine; N-Propionylglycine Di-TMS; Silylated Propionylglycine
EINECS	Contact for details

Quality Control

Our Propionylglycine, Di-Tms is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with your specifications. We support cGMP and ISO 9001 standards for research and commercial-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.