Description

(3Ar,4R,6E,9R,10Z,11Ar)-9-Acetoxy-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds known for their significant biological activity and structural complexity. This compound matters as a high-value intermediate or reference standard for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily needed by pharmaceutical R&D laboratories, biotechnology firms, and academic research institutions focused on oncology, anti-inflammatory, and other bioactive natural product-inspired drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex drug candidates, leveraging its intricate stereochemistry.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis (HPLC, LC-MS).
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies to develop new compounds with potential anticancer, antimicrobial, or anti-inflammatory properties.
• Natural Product Synthesis: Employed in total synthesis projects aimed at constructing complex natural products or their analogs for biological evaluation.
• Biochemical Research: Investigated for its potential to interact with specific biological targets and pathways in preclinical studies.

Basic Information

Product Name	(3Ar,4R,6E,9R,10Z,11Ar)-9-Acetoxy-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One
CAS No.	55520-20-2
Molecular Formula	C17H22O5
Molecular Weight	306.36 g/mol
Synonyms	9-Acetoxy-4-hydroxy-6,10-dimethyl-3-methylen-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one; 9-Acetoxy-4-hydroxy-6,10-dimethyl-3-methylene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one; (3aR,4R,6E,9R,10Z,11aR)-9-Acetoxy-4-hydroxy-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2-one; A sesquiterpene lactone acetate derivative
EINECS	Contact for details

Quality Control

Our (3Ar,4R,6E,9R,10Z,11Ar)-9-Acetoxy-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including HPLC for purity assay and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.