Description

1-(Trimethylsiloxy)-1,2,3-Propanetricarboxylic Acid Tris(Trimethylsilyl) Ester is a specialized organosilicon derivative of citric acid, primarily used as a key silylation reagent and synthetic intermediate. Its value lies in its ability to protect reactive functional groups, such as carboxylic acids and hydroxyls, facilitating purification and analysis in complex chemical syntheses. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for sensitive processes.

Application

• Derivatization Agent for GC/MS Analysis: Used to silylate polar organic compounds (acids, alcohols, amines) to improve their volatility and thermal stability for accurate gas chromatography and mass spectrometry.
• Pharmaceutical Intermediate: Serves as a protected form of citric acid or a silylating agent in the multi-step synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the synthesis of silicon-containing polymers, resins, and specialty coatings with tailored properties.
• Agrochemical Synthesis: Employed as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators where silicon incorporation is beneficial.
• Protecting Group in Organic Synthesis: Provides temporary protection for carboxylic acid groups during complex multi-step synthetic sequences, preventing unwanted side reactions.
• Standard & Reference Material: Used as a high-purity analytical standard or reference compound in quality control laboratories for method development and validation.

Basic Information

Product Name	1-(Trimethylsiloxy)-1,2,3-Propanetricarboxylic Acid Tris(Trimethylsilyl) Ester
CAS No.	55517-57-2
Molecular Formula	C18H40O7Si4
Molecular Weight	476.88 g/mol
Synonyms	Citric Acid Tris(trimethylsilyl) Ester Trimethylsilyl Ether; 1,2,3-Propanetricarboxylic Acid, 2-Hydroxy-, 1,3,5-Tris(trimethylsilyl) Ester, 2-(Trimethylsiloxy)-; Tris(trimethylsilyl) Citrate; TMS-Citrate; Trimethylsilyl Citrate; 2-(Trimethylsiloxy)-1,2,3-propanetricarboxylic Acid Tris(trimethylsilyl) Ester; Citric Acid TMS Derivative; Per(trimethylsilyl)citrate
EINECS	Contact for details

Quality Control

Our 1-(Trimethylsiloxy)-1,2,3-Propanetricarboxylic Acid Tris(Trimethylsilyl) Ester is manufactured under controlled conditions to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including GC, HPLC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.