Description

Biliverdin Dihydrochloride is a bile pigment and a key intermediate in the heme catabolic pathway. This compound is of significant value in biochemical research and pharmaceutical development due to its role as a precursor to bilirubin and its intrinsic antioxidant and signaling properties. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and diagnostic reagent industries.

Application

• Biochemical Research: Used as a standard and reagent in studies of heme oxygenase activity, bile pigment metabolism, and oxidative stress pathways.
• Pharmaceutical Intermediates: Serves as a critical starting material or intermediate in the synthesis of novel therapeutic agents and prodrugs.
• Diagnostic Reagents: Employed in the development and calibration of diagnostic kits and assays for liver function and metabolic disorders.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate cytoprotective mechanisms, anti-inflammatory effects, and cellular signaling.
• Antioxidant Research: Utilized in experimental models to study its potent antioxidant and potential anti-apoptotic properties.
• Enzyme Substrate: Acts as a substrate for enzymes like biliverdin reductase in enzymatic activity assays.

Basic Information

Product Name	Biliverdin Dihydrochloride
CAS No.	55482-27-4
Molecular Formula	C₃₃H₃₆N₄O₆·2HCl
Molecular Weight	657.57 g/mol (Free base: 584.66 g/mol)
Synonyms	Biliverdin hydrochloride; Biliverdin dihydrochloride salt; 3,18-Diethenyl-1,19,22,24-tetrahydro-2,7,13,17-tetramethyl-1,19-dioxo-21,24-dihydrobilin-8,12-dipropanoic acid dihydrochloride; IXα-Biliverdin dihydrochloride; Biliverdin IXα dihydrochloride; Verdins; 1,19-Dioxo-1,19,21,24-tetrahydrobilin-8,12-dipropanoic acid dihydrochloride
EINECS	Contact for details

Quality Control

Our Biliverdin Dihydrochloride is produced and handled under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to moisture and light. For long-term storage, consider desiccants and inert atmosphere.

Specification

Item	Specification
Appearance	Green to dark green crystalline powder
Identification (HPLC/UV-Vis)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.