Description

1,3-Dimethyl-1H-Pyrazole-5-Carbonyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 1,3-dimethylpyrazole-5-carbonyl moiety, a key structural motif in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for constructing complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and insecticides that incorporate pyrazole chemistry for enhanced efficacy.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials with specific optoelectronic properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke chemicals for client projects.
• Academic and R&D Laboratories: Fundamental reagent for methodological development in organic chemistry and the exploration of new heterocyclic compound libraries.

Basic Information

Product Name	1,3-Dimethyl-1H-Pyrazole-5-Carbonyl Chloride
CAS No.	55458-67-8
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	1,3-Dimethyl-1H-pyrazole-5-carbonyl chloride; 1,3-Dimethylpyrazole-5-carbonyl chloride; 5-Carboxy-1,3-dimethylpyrazole chloride; 1H-Pyrazole-5-carbonyl chloride, 1,3-dimethyl-; 1,3-Dimethyl-5-pyrazolecarbonyl chloride; 1,3-Dimethyl-1H-pyrazole-5-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl-1H-Pyrazole-5-Carbonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and agrochemical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.