Description

Isoxepac CAS NO 55453-87-7 is a non-steroidal anti-inflammatory drug (NSAID) derivative, specifically a benzoxepine acetic acid, known for its potent cyclooxygenase (COX) inhibitory activity. This compound serves as a critical pharmaceutical intermediate and a valuable reference standard in research and development. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of advanced drug candidates and for analytical quality control purposes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel anti-inflammatory and analgesic drug candidates.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of active pharmaceutical ingredients (APIs).
• Biochemical Research: A tool compound for studying COX enzyme inhibition mechanisms, inflammation pathways, and structure-activity relationships (SAR).
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized benzoxepine-based compounds.

Basic Information

Product Name	Isoxepac
CAS No.	55453-87-7
Molecular Formula	C16H14O4
Molecular Weight	270.28 g/mol
Synonyms	10,11-Dihydro-10-oxodibenzo[b,f]oxepin-2-acetic acid; 2-[10,11-Dihydro-10-oxodibenzo[b,f]oxepin-2-yl]acetic acid; Isoxepac; Wy-21,881; Wy 21881; Wy21881; Dibenzo[b,f]oxepin-2-acetic acid, 10,11-dihydro-10-oxo-
EINECS	Contact for details

Quality Control

Our Isoxepac is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity determination by HPLC, and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.