Description

Piperazine-1-Carboxylic Acid Allyl Ester is a versatile and reactive chemical intermediate featuring a piperazine core with a protected carboxylic acid group. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in pharmaceutical development. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of piperazine-containing active pharmaceutical ingredients (APIs), including potential candidates for neurological and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the piperazine moiety can contribute to biological activity.
• Peptide Mimetics & PROTACs: Serves as a component in the design of peptide mimetics and Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis and other advanced chemical transformations.
• Polymer Modification: The allyl ester group allows for incorporation into polymers via radical or cross-coupling reactions, enabling the creation of functional materials.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	Piperazine-1-Carboxylic Acid Allyl Ester
CAS No.	55389-48-5
Molecular Formula	C8H14N2O2
Molecular Weight	170.21 g/mol
Synonyms	1-Allyloxycarbonylpiperazine; Allyl 1-Piperazinecarboxylate; 1-(Allyloxycarbonyl)piperazine; Piperazine-1-carboxylic acid allyl ester; N-Allyloxycarbonylpiperazine; 1-CBz-Piperazine (Allyl); Allyl Piperazine-1-carboxylate; Fmoc-Piperazine-OH Allyl Ester precursor
EINECS	Contact for details

Quality Control

Our Piperazine-1-Carboxylic Acid Allyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.