Description

2-Depentylperhydrohistrionicotoxin is a complex, high-purity alkaloid derivative with a defined stereochemistry. This compound matters as a critical reference standard and advanced research chemical for neurobiological and pharmacological studies. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and specialty chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Neurological Research: Acts as a key reference compound for studying nicotinic acetylcholine receptor (nAChR) modulation and related signal transduction pathways.
• Pharmacological Development: Serves as a sophisticated synthetic intermediate or a comparative standard in the development of new therapeutic agents targeting the central nervous system.
• Analytical Chemistry: Used as a high-purity certified reference material (CRM) for method development and calibration in advanced chromatographic (HPLC, LC-MS) and spectroscopic analyses.
• Organic Synthesis: Provides a structurally complex scaffold for medicinal chemists exploring structure-activity relationships (SAR) in alkaloid-based drug discovery programs.

Basic Information

Item	Details
Product Name	2-Depentylperhydrohistrionicotoxin
CAS No.	55228-77-8
Molecular Formula	C15H25NO
Molecular Weight	235.37 g/mol
Synonyms	Perhydro-2-depentylhistrionicotoxin; 2-Depentyl-perhydro-histrionicotoxin; Histrionicotoxin analog; 2-DPHT; 1-Azabicyclo[5.3.0]decane, 2-hexyl-10-(2-hydroxypropyl)-; (1R,2R,6R,7S,8S,9S)-2-Hexyl-8-(2-hydroxypropyl)-1-azabicyclo[5.3.0]decane
EINECS	Contact for details

Quality Control

Our 2-Depentylperhydrohistrionicotoxin is produced under stringent conditions to ensure exceptional purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.