Description

Piperazine-2-Carboxylic Acid is a high-purity, non-proteinogenic amino acid derivative featuring a piperazine ring structure. This compound serves as a critical chiral building block and intermediate in sophisticated organic synthesis, enabling the development of complex molecules with high stereochemical fidelity. It is essential for research and production in the pharmaceutical industry, particularly for creating active pharmaceutical ingredients (APIs), peptidomimetics, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other complex drug molecules.
• Peptidomimetics & Bioactive Peptides: Used to incorporate constrained piperazine motifs into peptide backbones to enhance metabolic stability and receptor selectivity.
• Ligand & Catalyst Development: Serves as a precursor for creating chiral ligands used in asymmetric catalysis and metal complexation.
• Chemical Research & Development: A valuable building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Agrochemical Synthesis: Employed in the research and development of advanced, targeted crop protection agents.

Basic Information

Product Name	Piperazine-2-Carboxylic Acid
CAS No.	54969-33-4
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	D-Pipecolic Acid; (R)-Piperazine-2-carboxylic acid; (R)-Pipecolic Acid; D-Pipecolinic Acid; (R)-(-)-Pipecolic Acid; 2-Piperazinecarboxylic Acid; Hexahydropyridine-2-carboxylic Acid; (R)-2-Piperidinecarboxylic Acid
EINECS	Contact for details

Quality Control

Our Piperazine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.