Description

Methyl 3-Quinuclidinecarboxylate Hydrochloride is a high-purity organic salt derivative of the quinuclidine scaffold, serving as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. Its value lies in providing a rigid, nitrogen-containing bicyclic structure essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and acting as muscarinic receptor ligands.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the quinuclidine moiety can contribute to specific biological activity.
• Chemical Synthesis: Serves as a versatile precursor for creating complex molecules in medicinal chemistry and material science research.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Academic & R&D: Utilized in university and corporate research laboratories for studying structure-activity relationships (SAR) and novel synthetic pathways.

Basic Information

Product Name	Methyl 3-Quinuclidinecarboxylate Hydrochloride
CAS No.	54954-73-3
Molecular Formula	C9H16ClNO2
Molecular Weight	205.68 g/mol
Synonyms	3-Quinuclidinecarboxylic acid, methyl ester, hydrochloride; Methyl 3-quinuclidinecarboxylate HCl; Methyl quinuclidine-3-carboxylate hydrochloride; 1-Azabicyclo[2.2.2]octane-3-carboxylic acid, methyl ester, hydrochloride; 3-Carbomethoxyquinuclidine hydrochloride; Quinuclidine-3-carboxylic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl 3-Quinuclidinecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, residual solvents, and specific tests for this intermediate grade. Our quality commitment aligns with cGMP principles for pharmaceutical starting materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.