Description

1-Pyrazolidinecarbonyl Chloride, 2-Methyl-5-Oxo- (9Ci) is a specialized heterocyclic acid chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its high reactivity as an acylating agent, enabling the efficient introduction of the 2-methyl-5-oxopyrazolidine-1-carbonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its heterocyclic structure contributes to biological activity.
• Peptide Mimetics & Bioactive Molecule Construction: Serves as a versatile scaffold for creating peptidomimetics and other complex bioactive compounds.
• Material Science Research: Employed in the synthesis of specialized polymers and functional materials with tailored properties.
• Chemical Biology Probes: Utilized to create labeled compounds and probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-Pyrazolidinecarbonyl Chloride, 2-Methyl-5-Oxo- (9Ci)
CAS No.	54945-00-5
Molecular Formula	C5H7ClN2O2
Molecular Weight	162.57 g/mol
Synonyms	2-Methyl-5-oxopyrazolidine-1-carbonyl chloride; 1-(Chlorocarbonyl)-2-methyl-5-pyrazolidinone; 2-Methyl-5-oxo-1-pyrazolidinecarbonyl chloride; 2-Methyl-5-oxo-1H-pyrazole-1-carbonyl chloride (tautomeric form); 1-Carbamoyl-2-methyl-5-pyrazolidinone chloride; 2-Methyl-5-oxopyrazolidine carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1-Pyrazolidinecarbonyl Chloride, 2-Methyl-5-Oxo- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and good laboratory practice (GLP) standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent reactive compound, keep away from heat, open flames, and incompatible materials such as bases, amines, and alcohols. Use appropriate corrosion-resistant storage equipment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.