Description

11(S)-HETE is a specific stereoisomer of the hydroxyeicosatetraenoic acid family, a bioactive lipid mediator derived from arachidonic acid. This compound matters significantly in biochemical research as a key signaling molecule involved in inflammatory and vascular processes. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for use as a critical reference standard and a tool for studying eicosanoid pathways, receptor interactions, and disease mechanisms.

Application

• Biochemical Research Standard: Serves as a high-purity analytical reference standard for the quantification and identification of eicosanoids in biological samples via LC-MS/MS or HPLC.
• Inflammation & Immunology Studies: Used to investigate the role of specific HETE isomers in inflammatory cascades, leukocyte activation, and cytokine modulation.
• Cardiovascular Research: Applied in studies exploring the effects of lipid mediators on vascular tone, endothelial function, and atherosclerosis.
• Cell Signaling Pathway Analysis: A vital tool for elucidating G-protein-coupled receptor (GPCR) signaling pathways and downstream cellular responses.
• Drug Discovery & Development: Utilized in screening assays and validation studies for novel anti-inflammatory or cardiovascular therapeutic targets.
• Metabolomics & Lipidomics: An essential component in profiling lipid mediators to understand metabolic diseases and biomarker discovery.

Basic Information

Product Name	11(S)-HETE
CAS No.	54886-50-9
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	11(S)-HETE; 11S-HETE; (11S)-HETE; 11(S)-Hydroxyeicosa-5Z,8Z,12E,14Z-tetraenoic Acid; 11S-Hydroxyeicosatetraenoic Acid; 11-Hydroxy-5,8,12,14-eicosatetraenoic Acid; 11(S)-Hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic Acid; 11-HETE
EINECS	Contact for details

Quality Control

Our 11(S)-HETE is manufactured under strict quality protocols to ensure the highest standards of purity and stereochemical integrity, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to relevant industry standards for fine chemicals and reference materials.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or film
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
11(S)-Isomer Content (Chiral HPLC)	≥ 98%
Solvent (if applicable)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.