Description

15(S)-Hete CAS NO 54845-95-3 is a high-purity, stereospecific hydroxy eicosatetraenoic acid (HETE) derivative, a significant bioactive lipid mediator. This compound is valued for its role as a key intermediate and reference standard in advanced biochemical and pharmacological research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require precise, well-characterized compounds for studying eicosanoid pathways, inflammation, and related metabolic processes.

Application

• Biochemical Research: Used as a critical reference standard and analytical standard in lipidomics and eicosanoid research.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) precursor in the development of novel anti-inflammatory and immunomodulatory drugs.
• Cell Signaling Studies: Employed in vitro and in vivo to investigate the mechanisms of action of 15(S)-HETE in cellular signaling pathways.
• Enzyme Activity Assays: Utilized as a substrate or inhibitor in assays for lipoxygenase and other related enzymes.
• Metabolite Analysis: Acts as a calibration standard in mass spectrometry (LC-MS/MS, GC-MS) for the quantitative analysis of HETE metabolites in biological samples.
• Academic Research: Fundamental tool for universities and research institutes studying cardiovascular, pulmonary, and oncological disease models.

Basic Information

Product Name	15(S)-Hete
CAS No.	54845-95-3
Molecular Formula	C20H32O3
Molecular Weight	320.47 g/mol
Synonyms	15(S)-HETE; 15S-HETE; (15S)-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15(S)-Hydroxyeicosatetraenoic Acid; 15S-Hydroxy-5,8,11,13-eicosatetraenoic Acid; 15S-Hydroxyicosatetraenoic Acid; 15-HETE (S-isomer)
EINECS	Contact for details

Quality Control

Our 15(S)-Hete is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material suitable for use under cGMP conditions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep desiccated to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow oil or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95% (Area %)
Purity (HPLC)	≥ 98% (Total)
Enantiomeric Purity (Chiral HPLC)	≥ 99% (15S-isomer)
Solubility	Soluble in ethanol, DMSO, and organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.