Description

[5-(4-Methoxy-2,3,6-Trimethylphenyl)-3-Methyl-2,4-Pentadien-1-Yl]Triphenylphosphonium Bromide is a high-purity, specialized Wittig reagent salt, essential for advanced organic synthesis. Its core value lies in enabling the precise construction of complex polyene structures, a critical step in the synthesis of fine chemicals and active pharmaceutical ingredients (APIs). This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing key molecular frameworks. The product is supplied with a guaranteed Certificate of Analysis to ensure batch-to-batch consistency and reliability for sensitive synthetic applications.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the Wittig olefination reaction in the synthesis of complex vitamin analogs, retinoids, and other polyene-containing drug molecules.
• Agrochemical Research: Used in building conjugated diene and triene systems found in certain pheromones and bioactive natural product derivatives.
• Advanced Material Precursors: Employed in the synthesis of organic semiconductors and light-harvesting materials where controlled polyene chain length is crucial.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry and for constructing challenging carbon-carbon double bonds in total synthesis projects.
• Fine Chemical Production: Facilitates the scalable production of specialty chemicals requiring specific stereochemistry and conjugation patterns.

Basic Information

Product Name	[5-(4-Methoxy-2,3,6-Trimethylphenyl)-3-Methyl-2,4-Pentadien-1-Yl]Triphenylphosphonium Bromide
CAS No.	54757-44-7
Molecular Formula	C36H38BrOP
Molecular Weight	597.57 g/mol
Synonyms	(5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methylpenta-2,4-dien-1-yl)triphenylphosphonium bromide; (E,E)-[5-(4-Methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadienyl]triphenylphosphonium bromide; Trimethylmethoxyphenylpentadienyltriphenylphosphonium bromide; Wittig Salt 54757-44-7; Phosphonium salt, [5-(4-methoxy-2,3,6-trimethylphenyl)-3-methyl-2,4-pentadien-1-yl]triphenyl-, bromide; Polyene phosphonium salt intermediate.
EINECS	Contact for details

Quality Control

Our [5-(4-Methoxy-2,3,6-Trimethylphenyl)-3-Methyl-2,4-Pentadien-1-Yl]Triphenylphosphonium Bromide is manufactured under strict quality control protocols to ensure high chemical purity and lot-to-lot consistency suitable for research and process chemistry. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay (HPLC/NMR), identity confirmation, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical development partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.