Description

(2R,3S,4R,5E)-5-[(2,4-Dinitrophenyl)Hydrazinylidene]Hexane-1,2,3,4,6-P Entol is a specialized chiral compound featuring a hydrazone functional group derived from a 2,4-dinitrophenylhydrazine (DNPH) moiety. This molecular architecture makes it a valuable intermediate and analytical reference standard for research and quality control in advanced chemical synthesis. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring high-purity, stereochemically defined building blocks. The compound's defined stereochemistry and reactive hydrazinylidene group are critical for developing targeted molecular probes and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel therapeutic agents, particularly where specific stereochemistry is required for biological activity.
• Analytical Reference Standard: Used in High-Performance Liquid Chromatography (HPLC) and mass spectrometry for method development, calibration, and quantification of related compounds or degradation products.
• Biochemical Research: Employed as a derivatization agent or molecular probe in studying enzyme interactions, protein binding, and metabolic pathways due to its hydrazone functionality.
• Fine Chemical Synthesis: Acts as a precursor for the synthesis of more complex molecules in agrochemicals, dyes, and advanced materials research.
• Quality Control & Compliance: Essential for analytical laboratories to ensure the identity, purity, and strength of pharmaceutical products and chemical batches in compliance with GMP guidelines.

Basic Information

Product Name	(2R,3S,4R,5E)-5-[(2,4-Dinitrophenyl)Hydrazinylidene]Hexane-1,2,3,4,6-P Entol
CAS No.	54538-24-8
Molecular Formula	C12H14N4O6P (Tentative - Contact for confirmation)
Molecular Weight	Contact for details
Synonyms	5-[(2,4-Dinitrophenyl)hydrazono]hexane-1,2,3,4,6-pentol derivative; DNPH derivative of a hexose; (5E)-5-[(2,4-Dinitrophenyl)hydrazinylidene]hexane-1,2,3,4,6-pentol phosphate; Entol DNPH adduct; Chiral dinitrophenylhydrazone; Carbohydrate-DNPH conjugate; 2,4-DNPH derivative of a phosphorylated aldose
EINECS	Contact for details

Quality Control

Every batch of (2R,3S,4R,5E)-5-[(2,4-Dinitrophenyl)Hydrazinylidene]Hexane-1,2,3,4,6-P Entol is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing specific test results—including assay (HPLC), chiral purity, and identification—is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled to minimize exposure to moisture and air to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% de (by Chiral HPLC)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.