Description

3-(3-Thienyl)-Acryloyl Chloride is a specialized organic building block featuring a reactive acid chloride group conjugated to a thiophene ring. This compound matters as a key intermediate for introducing the 3-thienylacryloyl moiety into target molecules, enabling the synthesis of novel materials and active compounds. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, polymer chemistry, and ligand synthesis.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring a thiophene-based pharmacophore.
• Agrochemical Synthesis: Serves as a precursor for creating novel herbicides, fungicides, and insecticides with potential enhanced activity.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing functional polymers, conductive materials, and specialty coatings.
• Ligand & Chelator Preparation: Employed in the development of novel ligands for catalysis or metal chelation in industrial and research chemistry.
• Organic Synthesis Building Block: Utilized in amide coupling reactions (e.g., with amines) to create a wide array of amide derivatives for further chemical exploration.
• Research & Development: A valuable reagent for academic and industrial R&D labs exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	3-(3-Thienyl)-Acryloyl Chloride
CAS No.	54449-42-2
Molecular Formula	C7H5ClOS
Molecular Weight	172.63 g/mol
Synonyms	3-(3-Thienyl)acryloyl chloride; 3-Thiopheneacryloyl chloride; (E)-3-(Thiophen-3-yl)acryloyl chloride; 3-(3-Thienyl)propenoyl chloride; 3-Thienylacrylic acid chloride; trans-3-(3-Thienyl)acryloyl chloride; 3-Thenoic acid, 2-propenoyl chloride; 54449-42-2
EINECS	Contact for details

Quality Control

Our 3-(3-Thienyl)-Acryloyl Chloride undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Light yellow to brown liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.