Description

(1R,3Aβ,6Aβ)-Dodecahydro-1-Ethyl-9Aβ-Methylpyrido[2,1,6-De]Quinolizin-2β-Ol Acetate CAS NO 54352-65-7 is a complex, high-purity alkaloid derivative with a defined stereochemistry, making it a valuable chiral building block and reference standard. This compound matters for its role in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new drug candidates, especially within the fields of neurology and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of complex drug molecules, particularly those with neurological activity.
• Reference Standard: Used as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore new pharmacophores and optimize drug efficacy and selectivity.
• Asymmetric Synthesis: Utilized as a starting material or template in catalytic asymmetric reactions to construct complex molecular architectures.
• Biochemical Research: Acts as a ligand or probe in studying receptor interactions and enzyme mechanisms relevant to neurological pathways.
• Fine Chemical Production: Integrated into multi-step synthesis processes for the manufacture of specialized, high-value chemical entities.

Basic Information

Product Name	(1R,3Aβ,6Aβ)-Dodecahydro-1-Ethyl-9Aβ-Methylpyrido[2,1,6-De]Quinolizin-2β-Ol Acetate
CAS No.	54352-65-7
Molecular Formula	C19H31NO2
Molecular Weight	305.46 g/mol
Synonyms	1-Ethyl-9a-methyl-2b-acetoxypyrido[2,1,6-de]quinolizidine; 2β-Acetoxy-1-ethyl-9a-methylpyrido[2,1,6-de]quinolizidine; (1R,3aβ,6aβ)-1-Ethyl-9aβ-methyl-2β-acetoxyoctahydro-1H-pyrido[2,1,6-de]quinolizine; 54352-65-7; A specific stereoisomer of a quinolizidine alkaloid derivative. Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our (1R,3Aβ,6Aβ)-Dodecahydro-1-Ethyl-9Aβ-Methylpyrido[2,1,6-De]Quinolizin-2β-Ol Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research and pharmaceutical intermediate standards. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.