Description

5-Thiazolecarbonyl Chloride, 4-Methyl- (9Ci) is a specialized heterocyclic building block and key acyl chloride intermediate. Its value lies in enabling the efficient synthesis of complex amides and esters, which are crucial for developing advanced active ingredients. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel molecules and fine-tuning product properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel thiazole-containing drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the thiazole moiety can confer specific biological activity.
• Material Science Research: Serves as a precursor for functional polymers or liquid crystals that incorporate heterocyclic units for enhanced properties.
• Peptide Mimetics & Bioconjugation: Facilitates the introduction of the 4-methylthiazole group into peptides or other biomolecules to modify their structure and function.
• Chemical Biology Probes: Employed in the creation of molecular probes and labeling reagents for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical raw material for fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	5-Thiazolecarbonyl Chloride, 4-Methyl- (9Ci)
CAS No.	54237-09-1
Molecular Formula	C5H4ClNOS
Molecular Weight	161.61 g/mol
Synonyms	4-Methylthiazole-5-carbonyl chloride; 4-Methyl-1,3-thiazole-5-carbonyl chloride; 4-Methyl-5-thiazolecarbonyl chloride; 5-Carboxy-4-methylthiazole chloride; 4-Methylthiazole-5-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Thiazolecarbonyl Chloride, 4-Methyl- (9Ci) is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.