Description

Uroporphyrin I Ethyl Ester is a high-purity, chemically defined porphyrin derivative essential for advanced biochemical research and diagnostic development. This compound serves as a critical reference standard and synthetic intermediate for studying heme biosynthesis, porphyrias, and photodynamic processes. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and manufacturers of in-vitro diagnostic kits requiring precise molecular tools.

Application

• Biochemical Research Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of porphyrins and their metabolites in biological samples.
• Porphyria Diagnostics: Serves as a key calibrant and control in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) methods for the diagnosis of congenital erythropoietic porphyria and other porphyrin disorders.
• Photodynamic Therapy (PDT) Research: Investigated as a precursor or model compound for the development of new photosensitizers in cancer treatment research.
• Enzyme Activity Studies: Employed as a substrate or inhibitor in assays for enzymes involved in the heme biosynthesis pathway, such as uroporphyrinogen decarboxylase.
• Analytical Method Development: Essential for validating and optimizing chromatographic separation techniques and spectroscopic methods for porphyrin analysis.
• Chemical Synthesis: Acts as a protected intermediate in the multi-step synthesis of more complex porphyrin analogs and conjugates for specialized applications.

Basic Information

Product Name	Uroporphyrin I Ethyl Ester
CAS No.	54090-85-6
Molecular Formula	C₅₂H₅₈N₄O₁₆
Molecular Weight	994.04 g/mol
Synonyms	Uroporphyrin I octaethyl ester; 3,7,13,17-Tetrakis(2-carboxyethyl)-2,8,12,18-tetramethylporphyrin octaethyl ester; Uroporphyrinogen I octaethyl ester (oxidized form); URO I EE; Octaethyl uroporphyrin I; Uroporphyrin-1-octaethyl ester
EINECS	Contact for details

Quality Control

Our Uroporphyrin I Ethyl Ester is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results from HPLC, NMR, and mass spectrometry. We adhere to ISO 9001 quality management principles, and our processes are designed to meet the exacting standards required for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider keeping the product under an inert atmosphere (e.g., argon or nitrogen) to prevent potential oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark red to purple solid
Identification (HPLC)	Conforms to reference standard
Identification (UV-Vis)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in chloroform, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.