Description

16β-Acetoxy-3β,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide is a high-purity bufadienolide derivative, a specialized class of steroidal compounds with significant biological activity. This compound is valued for its role as a critical pharmaceutical intermediate and reference standard in advanced research and development. It is primarily utilized by pharmaceutical manufacturers and biotechnology research organizations engaged in the synthesis of novel therapeutic agents and detailed pharmacological studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel cardioactive and anticancer drug candidates.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related substances.
• Biochemical Research: Employed in pharmacological studies to investigate structure-activity relationships (SAR) of bufadienolides.
• Academic Research: Serves as a pure compound for university and institutional research into natural product chemistry and medicinal chemistry.
• Preclinical Development: Utilized in the early-stage development of new chemical entities (NCEs) for various therapeutic targets.

Basic Information

Product Name	16β-Acetoxy-3β,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide
CAS No.	53823-14-6
Molecular Formula	C₂₆H₃₂O₈
Molecular Weight	472.53 g/mol
Synonyms	19-Oxobufalin 16-acetate; 16β-Acetoxy-3β,14-dihydroxy-19-oxobufa-4,20,22-trienolide; 19-Oxobufalin-16-acetate; 3β,14,16β-Trihydroxy-19-oxobufa-4,20,22-trienolide 16-acetate; Bufadienolide derivative; 53823-14-6; SCHEMBL2180551
EINECS	Contact for details

Quality Control

Our 16β-Acetoxy-3β,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.