Description

Insulin, Carbonyl-Bis-Met,N(Alphal),N(Epsilon)(B29)- CAS NO 53800-33-2 is a chemically modified derivative of insulin, specifically a bis-methylated adduct at the B29 lysine residue. This compound is of significant value in biochemical and pharmaceutical research for studying insulin structure-function relationships, stability, and receptor interactions. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in advanced diabetes research and the development of novel insulin analogs or diagnostic tools.

Application

• Biochemical Research: Used as a key reference standard and tool compound for investigating insulin's biological activity and metabolic pathways.
• Pharmaceutical Development: Serves as an intermediate or model compound in the research and development of new insulin-based therapeutics with modified pharmacokinetic profiles.
• Analytical Standard: Employed as a high-purity standard in chromatographic (HPLC, LC-MS) and spectroscopic analyses for method development and quality control of insulin products.
• Structure-Activity Relationship (SAR) Studies: Critical for mapping the impact of specific chemical modifications on insulin's binding affinity and biological potency.
• Proteomics & Metabolic Studies: Utilized in specialized studies to understand post-translational modifications and their effects on protein function.

Basic Information

Product Name	Insulin, Carbonyl-Bis-Met,N(Alphal),N(Epsilon)(B29)-
CAS No.	53800-33-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	B29-Bis-Methyl Insulin; N(alpha),N(epsilon)-Bis-methyl Insulin B29; Carbonyl-Bis-Methyl Insulin; Insulin B29 Methylated Derivative; Modified Insulin (B29-bis-methyl); Insulin Adduct (B29); Research Insulin Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. For this research-grade biochemical, quality is assured through advanced analytical techniques including HPLC and mass spectrometry to confirm identity and purity, meeting the exacting requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term stability, consider storage at -20°C under desiccant.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.