Description

(3S,4R)-3-Methyl-4-n-Phenylamino-Piperidine is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical synthesis. Its defined stereochemistry makes it an essential intermediate for developing active pharmaceutical ingredients (APIs) with specific biological activity. This compound is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in central nervous system (CNS) and receptor-targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• Asymmetric Synthesis: Serves as a chiral auxiliary or precursor in stereoselective synthesis routes.
• Ligand and Receptor Studies: Employed in the development of compounds targeting specific neurological and biological pathways.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Preclinical Development: Supplied for use in the synthesis of compounds for pharmacological and toxicological evaluation.

Basic Information

Product Name	(3S,4R)-3-Methyl-4-n-Phenylamino-Piperidine
CAS No.	53757-51-0
Molecular Formula	C12H18N2
Molecular Weight	190.29 g/mol
Synonyms	(3S,4R)-3-Methyl-4-(phenylamino)piperidine; 4-(Phenylamino)-3-methylpiperidine, (3S,4R)-; (3S,4R)-3-Methyl-4-anilinopiperidine; 3-Methyl-4-(phenylamino)piperidine (stereoisomer); 1-Phenyl-3-methyl-4-aminopiperidine derivative; 4-Anilino-3-methylpiperidine; (3S-cis)-3-Methyl-4-(phenylamino)piperidine; A potential pharmaceutical intermediate code
EINECS	Contact for details

Quality Control

Our (3S,4R)-3-Methyl-4-n-Phenylamino-Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.