Description

Methyl (2E)-(3-Oxopiperazin-2-Ylidene)Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its piperazinone core structure. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research and development. Pharmaceutical manufacturers and fine chemical R&D laboratories need this material for constructing novel drug candidates targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those containing piperazine or piperazinone pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing novel chemical libraries and exploring structure-activity relationships (SAR) in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for potential use in central nervous system (CNS), anti-infective, or other therapeutic agents.
• Fine Chemical Production: Employed in the manufacture of specialty and custom fine chemicals where its unique reactive sites allow for further functionalization.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	Methyl (2E)-(3-Oxopiperazin-2-Ylidene)Acetate
CAS No.	53700-43-9
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	Methyl (2E)-2-(3-oxopiperazin-2-ylidene)acetate; 2-(3-Oxo-2-piperazinylidene)acetic acid methyl ester; Methyl 2-(3-oxo-2-piperazinylidene)acetate; (2E)-Methyl 2-(3-oxopiperazin-2-ylidene)acetate; 2-Piperazinone, 2-(methoxycarbonylmethylene)-; Methyl (2E)-(3-oxo-2-piperazinylidene)ethanoate
EINECS	Contact for details

Quality Control

Our Methyl (2E)-(3-Oxopiperazin-2-Ylidene)Acetate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development and commercial projects requiring material that meets stringent internal specifications or compendial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.