Description

Isobrucein B CAS NO 53663-03-9 is a highly bioactive limonoid compound, a member of the quassinoid family, known for its significant pharmacological properties. This compound is of critical importance for research and development in the pharmaceutical and life sciences sectors due to its potent biological activities. It is primarily sought by researchers and manufacturers focused on oncology, parasitology, and natural product chemistry for use as a reference standard, a lead compound in drug discovery, and in mechanistic studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutic agents.
• Anticancer Agent Studies: Utilized in in vitro and in vivo research to investigate its cytotoxic and antiproliferative effects against various cancer cell lines.
• Antiparasitic Drug Discovery: Employed as a lead compound in the search for new treatments against parasitic diseases, leveraging its potent antimalarial and antihelmintic potential.
• Natural Product Isolation & Analysis: Used as a high-purity analytical standard for the identification and quantification of Isobrucein B and related compounds in plant extracts and complex matrices.
• Biochemical Pathway Investigation: Applied in cellular and molecular biology to study its mechanisms of action, including apoptosis induction and signal pathway modulation.
• Academic & Institutional Research: Essential for universities and research institutes conducting fundamental studies on quassinoids and their structure-activity relationships.

Basic Information

Product Name	Isobrucein B
CAS No.	53663-03-9
Molecular Formula	C₂₀H₂₄O₉
Molecular Weight	408.40 g/mol
Synonyms	Isobruceine B; Bruceine J; 6α-Tigloyloxychaparrinone; (1S,2R,4aS,6aR,7R,8S,8aS,8bS)-1,2,6a,7,8-Pentahydroxy-8a-(hydroxymethyl)-4a,8b-dimethyl-3,4,5,6,6a,7,8,8b,9,10-decahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-11(2H)-one 6-acetate 2-methylbutanoate; NSC 165563
EINECS	Contact for details

Quality Control

Our Isobrucein B is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.