Description

Etoformin Hydrochloride is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) with significant therapeutic potential. Its primary value lies in its role as a key building block for the synthesis of novel biguanide derivatives, which are of major interest in metabolic and oncological research. This compound is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new drug candidates, particularly for applications in diabetes and cancer research. CAS NO 53597-26-5.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of advanced biguanide-based active pharmaceutical ingredients (APIs).
• Metabolic Research: Used as a reference standard and experimental compound in studies targeting metabolic pathways, including diabetes and insulin resistance.
• Oncology Research: Investigated for its potential anti-proliferative and chemotherapeutic properties in preclinical cancer research models.
• Fine Chemical Synthesis: Employed in organic synthesis for constructing complex molecules with guanidine or biguanide functional groups.
• Biochemical Tool Compound: Utilized in vitro to study cellular mechanisms related to energy metabolism and mitochondrial function.
• Reference Standard: Provides a high-purity benchmark for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	Etoformin Hydrochloride
CAS No.	53597-26-5
Molecular Formula	C5H13N5•HCl
Molecular Weight	195.66 g/mol
Synonyms	1-(2-Phenylethyl)biguanide Hydrochloride; Phenethylbiguanide Hydrochloride; Etoformin HCl; N-Phenethylbiguanide Hydrochloride; NSC 10483; Phenformin Impurity; Phenformin Related Compound
EINECS	Contact for details

Quality Control

Our Etoformin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by FT-IR and NMR, to ensure it meets stringent specifications for research and pharmaceutical use. Certificates of Analysis (COA) with batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.