Description

Pentafluorophenyl(Phenyl)Fluorophosphine Oxide is a specialized organophosphorus compound featuring a pentafluorophenyl group, making it a valuable fluorinated building block. This compound is critical for introducing unique electronic and steric properties into advanced materials and active pharmaceutical ingredients. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials sectors for applications in catalysis and as a key synthetic intermediate.

Application

• As a ligand precursor in transition metal catalysis for cross-coupling reactions.
• As a key fluorinated synthon in the synthesis of novel active pharmaceutical ingredients (APIs).
• In the research and development of advanced agrochemicals and pesticides.
• For the preparation of functionalized materials, such as flame retardants or specialty polymers.
• As a reactive intermediate in organofluorine chemistry and phosphorus chemistry research.
• In the synthesis of potential ligands for metal-organic frameworks (MOFs) and other porous materials.

Basic Information

Product Name	Pentafluorophenyl(Phenyl)Fluorophosphine Oxide
CAS No.	53381-03-6
Molecular Formula	C12H5F6OP
Molecular Weight	310.13 g/mol
Synonyms	Pentafluorophenyl(phenyl)phosphinic fluoride; Fluorophenyl(pentafluorophenyl)phosphine oxide; (Pentafluorophenyl)phenylphosphinic fluoride; Phenyl(pentafluorophenyl)phosphinic fluoride; (Pentafluorophenyl)(phenyl)phosphoryl fluoride; 53381-03-6; Pentafluorophenyl phenylfluorophosphine oxide
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl(Phenyl)Fluorophosphine Oxide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity and identity is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive and easily oxidized nature, it is recommended to handle and store this material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹H NMR	Conforms to structure
³¹P NMR	Conforms to structure
¹⁹F NMR	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.