Description

(1,1-Dimethylethyl)(Pentafluorophenyl)Fluorophosphine Oxide is a specialized organophosphorus compound featuring a pentafluorophenyl group and a tert-butyl substituent. This structure makes it a valuable reagent and intermediate in advanced synthetic chemistry, particularly for introducing fluorinated phosphine oxide moieties. It is primarily used by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those targeting kinase inhibition or requiring fluorinated scaffolds.
• Agrochemical Research: Used to create novel fluorinated phosphine oxide ligands and active ingredients for crop protection chemicals.
• Ligand Synthesis: Serves as a precursor for specialized phosphine oxide ligands used in catalysis and materials science.
• Organic Synthesis Reagent: Employed in fluorination reactions and as a coupling partner in cross-coupling methodologies to construct complex molecules.
• Materials Science: Intermediate in the development of fluorinated polymers and advanced materials with specific electronic or surface properties.

Basic Information

Product Name	(1,1-Dimethylethyl)(Pentafluorophenyl)Fluorophosphine Oxide
CAS No.	53381-02-5
Molecular Formula	C10H9F6OP
Molecular Weight	290.15 g/mol
Synonyms	tert-Butyl(pentafluorophenyl)fluorophosphine oxide; Pentafluorophenyl tert-butylfluorophosphine oxide; tert-Butylpentafluorophenylfluorophosphine oxide; Fluorotert-butyl(pentafluorophenyl)phosphine oxide; (Pentafluorophenyl)(tert-butyl)fluorophosphine oxide; 2-Methyl-2-(pentafluorophenyl)fluorophosphorylpropane; TBPPFO
EINECS	Contact for details

Quality Control

Every batch of (1,1-Dimethylethyl)(Pentafluorophenyl)Fluorophosphine Oxide is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to moisture and strong bases; keep the container tightly sealed under an inert atmosphere such as argon or nitrogen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.