Description

Pseudo Uridine Penta-Tms is a key protected nucleoside derivative, specifically the pentakis(trimethylsilyl) ether of pseudouridine. This compound is essential for advanced organic synthesis and research, offering a stable, silylated intermediate for precise chemical modifications. It is primarily utilized by researchers and manufacturers in the fields of nucleoside chemistry, pharmaceutical development, and biochemical research.

Application

• Nucleoside Analogue Synthesis: A crucial protected intermediate for the chemical synthesis of modified nucleosides and nucleotides.
• Pharmaceutical Research: Used in the development and study of novel therapeutic agents, including antiviral and anticancer compounds.
• Biochemical Labeling & Probes: Serves as a precursor for creating labeled nucleosides used in diagnostic assays and molecular biology research.
• tRNA Modification Studies: Applied in research focused on understanding the role and biosynthesis of pseudouridine in RNA structure and function.
• Organic Synthesis Building Block: Provides a versatile, silyl-protected scaffold for complex multi-step synthetic routes in medicinal chemistry.

Basic Information

Product Name	Pseudo Uridine Penta-Tms
CAS No.	53294-25-0
Molecular Formula	C26H56N2O6Si5
Molecular Weight	625.22 g/mol
Synonyms	5-β-D-Ribofuranosyluracil, pentakis(trimethylsilyl) ether; Pseudouridine, pentakis-O-(trimethylsilyl)-; Pseudouridine pentatrimethylsilyl ether; ψ-TMS; 5-(β-D-Ribofuranosyl)uracil pentatrimethylsilyl derivative; 5-Ribosyluracil pentakis(trimethylsilyl) ether; Pseudouridine, TMS derivative
EINECS	Contact for details

Quality Control

Our Pseudo Uridine Penta-Tms is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.