Description

5-Hexynoic Acid is a versatile terminal alkyne carboxylic acid, serving as a critical bifunctional building block in advanced organic synthesis. Its unique structure, featuring both a reactive alkyne group and a carboxylic acid moiety, makes it indispensable for constructing complex molecular architectures through click chemistry and cross-coupling reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key starting material for synthesizing active pharmaceutical ingredients (APIs) and prodrugs via amide bond formation or esterification.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with tailored properties.
• Polymer & Material Science: Monomer for producing specialty polyesters, polyamides, and functional polymers with alkyne side chains for further modification.
• Bioconjugation & Probe Development: Used in click chemistry (e.g., CuAAC reactions) to label biomolecules, create diagnostic probes, and develop targeted drug delivery systems.
• Ligand & Catalyst Preparation: Precursor for synthesizing specialized ligands and organometallic catalysts used in homogeneous catalysis.
• Organic Synthesis: Versatile reagent for carbon-carbon bond formation, chain elongation, and the synthesis of complex natural product analogs.

Basic Information

Product Name	5-Hexynoic Acid
CAS No.	53293-00-8
Molecular Formula	C6H8O2
Molecular Weight	112.13 g/mol
Synonyms	5-Hexynoic Acid; 5-Hexyn-1-oic Acid; Hex-5-ynoic Acid; 4-Carboxy-1-butyne; 5-Hexynic Acid; Pentyl-1-yn-5-oic Acid; Terminal Alkyne Carboxylic Acid C6
EINECS	Contact for details

Quality Control

Our 5-Hexynoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee consistent quality and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.