Description

Phorbol 16-Hydroxy 12-Palmitate 13-Acetate is a specific, high-purity derivative of the phorbol diterpene family, a class of compounds known for their potent biological activity. This compound is critical for advanced biochemical and pharmacological research, serving as a precise molecular tool for studying protein kinase C (PKC) signaling pathways and related cellular mechanisms. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in cancer research, inflammation studies, and the development of novel therapeutic agents.

Application

• Biochemical Research: As a reference standard and active agent in studies of protein kinase C (PKC) activation and modulation.
• Pharmacological Studies: Used in vitro and in vivo research to investigate tumor promotion, cell proliferation, and apoptosis.
• Drug Discovery: A key intermediate or tool compound in screening assays and the development of PKC-targeted therapies.
• Academic Research: Employed in university and institutional labs for fundamental studies in cell signaling and molecular biology.
• Toxicology: Used as a model compound to study the mechanisms of action of tumor-promoting agents.
• Reference Material: Serves as a high-purity certified reference material (CRM) for analytical method development and validation.

Basic Information

Product Name	Phorbol 16-Hydroxy 12-Palmitate 13-Acetate
CAS No.	53202-98-5
Molecular Formula	C40H64O8
Molecular Weight	672.9 g/mol
Synonyms	16-Hydroxyphorbol 12-palmitate 13-acetate; 12-Palmitoylphorbol 13-acetate 16-hydroxy; 16-Hydroxy-12-O-palmitoylphorbol-13-acetate; Phorbol 16-hydroxy-12-palmitate-13-acetate; 16-Hydroxy TPA; 16-Hydroxy-12-O-hexadecanoylphorbol-13-acetate; 16-Hydroxyphorbol-12-palmitate-13-acetate
EINECS	Contact for details

Quality Control

Our Phorbol 16-Hydroxy 12-Palmitate 13-Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support research compliance with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider desiccant and inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.