Description

Oleandrin is a potent cardiac glycoside isolated from the leaves of the oleander plant (Nerium oleander). This compound is of significant interest in biochemical and pharmacological research due to its specific mechanism of action on cellular sodium-potassium ATPase pumps. It is primarily utilized by research institutions, pharmaceutical development laboratories, and biotechnology companies engaged in the study of cardiac function, oncology, and novel therapeutic pathways.

Application

• Biochemical Research: Used as a standard or probe in studies investigating the function and inhibition of Na+/K+-ATPase enzymes.
• Pharmacological Studies: Serves as a key compound in preclinical research for exploring potential effects on cardiac cells and cancer cell lines.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, or TLC for the identification and quantification of oleandrin in complex matrices.
• Mechanism of Action Research: Fundamental tool for studying cell signaling pathways, apoptosis, and intracellular ion homeostasis.
• Natural Product Chemistry: Used in the isolation, characterization, and synthesis studies of cardiac glycosides.

Basic Information

Product Name	Oleandrin
CAS No.	53177-88-1
Molecular Formula	C32H48O9
Molecular Weight	576.73 g/mol
Synonyms	Neriantin; Oleandrine; Foliandrin; 16β-Acetyloxy-3β-[(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-14-hydroxycard-20(22)-enolide; Corrigen; NSC 253801; Anvirzel (as a component)
EINECS	Contact for details

Quality Control

Our Oleandrin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research purposes. Each lot is analyzed using advanced chromatographic and spectroscopic techniques to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, identification, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.