Description

Nα-L-Valyl-N1-[1-(1,2,3,4-Tetrahydro-6,7-Dimethoxy-2-Methylisoquinolin-1-Yl)Ethyl]Glycinamide is a specialized synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel bioactive molecules targeting neurological and cardiovascular pathways. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in drug discovery programs. The product's complex structure makes it a valuable building block for creating potential therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies to investigate receptor binding and enzyme inhibition mechanisms.
• Peptide Chemistry: Acts as a sophisticated building block in solid-phase or solution-phase peptide synthesis for creating complex peptide mimetics.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of active pharmaceutical ingredients (APIs) for clinical trials.
• Analytical Standard: Provides a high-purity standard for method development and validation in quality control laboratories using HPLC, LC-MS, or NMR.

Basic Information

Product Name	Nα-L-Valyl-N1-[1-(1,2,3,4-Tetrahydro-6,7-Dimethoxy-2-Methylisoquinolin-1-Yl)Ethyl]Glycinamide
CAS No.	53098-67-2
Molecular Formula	C21H32N4O4
Molecular Weight	404.51 g/mol
Synonyms	Nα-Valyl-N1-[1-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methylisoquinolin-1-yl)ethyl]glycinamide; L-Valyl-N-[1-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethyl]glycinamide; Glycinamide, N-L-valyl-N-[1-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)ethyl]-; (S)-2-((S)-2-Amino-3-methylbutanamido)-N-(1-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethyl)acetamide; Tetrahydroisoquinoline peptide derivative; CAS 53098-67-2
EINECS	Contact for details

Quality Control

Our Nα-L-Valyl-N1-[1-(1,2,3,4-Tetrahydro-6,7-Dimethoxy-2-Methylisoquinolin-1-Yl)Ethyl]Glycinamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and compliance with your research or cGMP needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.