Description

[1,1'-Biphenyl]-4-Acetic Acid, 2-Hydroxy-α-Methyl- is a specialized biphenyl derivative with a hydroxyacetic acid side chain, serving as a valuable chiral building block and synthetic intermediate. Its molecular architecture is critical for constructing complex molecules where precise stereochemistry and aromatic functionality are required. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and advanced materials sectors for applications in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of novel bioactive compounds.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex organic molecules, ligands, and catalysts in asymmetric synthesis.
• Material Science: Potential monomer or additive in the development of specialized polymers and liquid crystals due to its rigid biphenyl core.

Basic Information

Product Name	[1,1'-Biphenyl]-4-Acetic Acid, 2-Hydroxy-α-Methyl-
CAS No.	52806-89-0
Molecular Formula	C15H14O3
Molecular Weight	242.27 g/mol
Synonyms	2-(4-Biphenylyl)-2-hydroxypropionic acid; 2-Hydroxy-2-(4-phenylphenyl)propanoic acid; α-Methyl-4-biphenylacetic acid, 2-hydroxy-; 2-(4-Phenylphenyl)-2-hydroxypropanoic acid; (±)-2-Hydroxy-2-(4-phenylphenyl)propanoic acid; 4-Biphenylacetic acid, 2-hydroxy-α-methyl-; 2-Hydroxy-2-([1,1'-biphenyl]-4-yl)propanoic acid
EINECS	Contact for details

Quality Control

Our production of [1,1'-Biphenyl]-4-Acetic Acid, 2-Hydroxy-α-Methyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and chiral analysis to confirm identity, potency, and enantiomeric purity where specified. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Chiral Purity (if applicable)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.