Description

Emetine Hydrobromide is a high-purity alkaloid salt derived from ipecac root, primarily recognized for its potent biological activity. This compound is critical for research and development in the pharmaceutical and life sciences sectors, where precise chemical structure and purity are paramount. It is essential for researchers and manufacturers developing therapeutic agents and biochemical tools, particularly in the study of antiprotozoal mechanisms and cellular processes.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the study of anti-amoebic and antiprotozoal drugs.
• Biochemical Research: Used as a potent inhibitor of protein synthesis in eukaryotic cells for studying cellular metabolism and gene expression.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing via HPLC, LC-MS, or NMR.
• Academic & Clinical Studies: Utilized in university and institutional research for investigating parasitic diseases and related biochemical pathways.
• Veterinary Medicine Development: Investigated for potential applications in treating specific parasitic infections in animals.

Basic Information

Product Name	Emetine Hydrobromide
CAS No.	52714-87-1
Molecular Formula	C₂₉H₄₀N₂O₄ • HBr
Molecular Weight	553.56 g/mol
Synonyms	Emetine HBr; Emetine Hydrobromide Salt; Emetine Monohydrobromide; Ipecacuanha Alkaloid Hydrobromide; (2S,3R,11bS)-2-{[(1R)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-3-ethyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-ol Hydrobromide; NSC-33669; Cephaeline Methylether Hydrobromide
EINECS	Contact for details

Quality Control

Our Emetine Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR and NMR, purity assay by HPLC, and control of specific impurities. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.