Description

1-Methylpiperidine-4-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant piperidine derivative, primarily utilized as a key synthetic intermediate. Its value lies in providing a functionalized, nitrogen-containing scaffold essential for constructing complex molecules in medicinal chemistry. This compound is critically needed by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, especially those targeting neurological receptors.
• Organic Synthesis Reagent: Used to introduce the 1-methylpiperidine-4-carboxylate moiety into larger, more complex organic molecules.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for method development and exploratory chemistry.
• Agrochemical Synthesis: Potential intermediate in the development of advanced pesticides and herbicides that require specific heterocyclic structures.
• Ligand & Catalyst Preparation: Can be used to synthesize chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	1-Methylpiperidine-4-Carboxylic Acid Hydrochloride
CAS No.	52700-61-5
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	4-Piperidinecarboxylic acid, 1-methyl-, hydrochloride (1:1); 1-Methyl-4-piperidinecarboxylic acid hydrochloride; Isonipecotic acid, 1-methyl-, hydrochloride; 1-Methylisonipecotic acid hydrochloride; 1-Methylpiperidine-4-carboxylic acid HCl; 4-Carboxy-1-methylpiperidine hydrochloride; NSC 163049
EINECS	Contact for details

Quality Control

Our 1-Methylpiperidine-4-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.