Description

(4S,8R,13R,14S)-13-Methyl-17-Norkaur-15-Ene-3α,7β,14,18-Tetrol is a high-purity diterpenoid compound of significant interest in advanced chemical synthesis and life science research. Its unique tetracyclic kaurane skeleton and multiple hydroxyl groups make it a valuable chiral building block and a precursor for the synthesis of complex natural products and pharmaceutical intermediates. This compound is primarily sought by research institutions, pharmaceutical R&D departments, and specialty chemical manufacturers engaged in developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory or anti-cancer pathways.
• Chemical Synthesis Building Block: Utilized in complex organic synthesis for constructing diterpenoid-based natural products and analogs due to its defined stereochemistry.
• Biochemical Research: Acts as a reference standard or probe in studies investigating diterpene biosynthesis, enzyme mechanisms, and structure-activity relationships (SAR).
• Natural Product Chemistry: Used as a starting material for the semi-synthesis of other bioactive kaurane-type diterpenoids found in traditional medicinal plants.
• Academic Research: Employed in university and institutional labs for methodological development in stereoselective synthesis and total synthesis projects.

Basic Information

Item	Details
Product Name	(4S,8R,13R,14S)-13-Methyl-17-Norkaur-15-Ene-3α,7β,14,18-Tetrol
CAS No.	52667-18-2
Molecular Formula	C₁₉H₃₀O₄
Molecular Weight	322.44 g/mol
Synonyms	13-Methyl-17-norkaur-15-ene-3α,7β,14,18-tetrol; 3α,7β,14,18-Tetrahydroxy-13-methyl-17-norkaur-15-ene; Ent-3α,7β,14,18-Tetrahydroxy-13-methyl-17-norkaur-15-ene; 7β-Hydroxy-3-oxo-ent-kaur-15-en-18-oic acid (related derivative); Kaurane diterpenoid tetraol; 17-Norkaurane tetraol derivative; NSC 403169; A tetracyclic diterpene alcohol.
EINECS	Contact for details

Quality Control

Our (4S,8R,13R,14S)-13-Methyl-17-Norkaur-15-Ene-3α,7β,14,18-Tetrol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and spectroscopic identification (NMR, IR, MS). A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support custom synthesis and purification to meet specific research or development grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.