Description

Aplysiatoxin CAS NO 52659-57-1 is a potent bioactive marine natural product belonging to the class of polyketide toxins. This compound is of significant interest in biochemical and pharmacological research due to its role as a potent activator of protein kinase C (PKC). It serves as a critical tool for researchers in life sciences, toxicology, and drug discovery, enabling the study of cellular signaling pathways, tumor promotion, and ion channel modulation.

Application

• Biochemical Research: As a high-affinity ligand and activator of Protein Kinase C (PKC) isoforms for studying signal transduction mechanisms.
• Pharmacological Studies: Used as a reference standard and probe in investigations of tumor promotion, inflammation, and cellular proliferation.
• Neuroscience Research: Tool compound for studying the modulation of ion channels and neuronal excitability.
• Toxicology and Environmental Monitoring: Reference material for the detection and analysis of marine algal toxins in water and seafood samples.
• Drug Discovery: Serves as a lead compound or molecular scaffold for the development of novel therapeutic agents targeting PKC.
• Academic and Institutional Research: Essential reagent for universities and research institutes focusing on marine natural products and their biological activities.

Basic Information

Item	Details
Product Name	Aplysiatoxin
CAS No.	52659-57-1
Molecular Formula	C32H47BrO10
Molecular Weight	671.62 g/mol
Synonyms	Aplysiatoxin; Debromoaplysiatoxin; 3-Bromo-5-[(1S,2S,4aS,6R,7S,8S,8aR)-7-hydroxy-2,6,8-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-2-methoxy-4,6-dimethylbenzoic acid; Marine toxin; PKC activator; Lyngbyatoxin-a congener
EINECS	Contact for details

Quality Control

Our Aplysiatoxin is produced and handled under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and structural verification by NMR and MS. A Certificate of Analysis (COA) detailing purity, identity, and batch-specific data is provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider under an inert atmosphere. Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.