Description

5-(Aminosulphonyl)-2-Methoxybenzoyl Chloride is a specialized aromatic acid chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its dual functional groups, enabling precise chemical modifications for creating complex molecular architectures. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel sulfonamide-containing active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including diuretics, carbonic anhydrase inhibitors, and anti-glaucoma agents.
• Agrochemical Synthesis: Used in the development of new generation herbicides and fungicides that leverage the sulfonylurea or sulfonamide moiety for enhanced activity.
• Dye & Pigment Manufacturing: Acts as a reactive intermediate for introducing sulfonamide and benzoyl groups into chromophore structures, improving solubility and fastness properties.
• Material Science Research: Employed in the creation of specialty polymers and functional materials, such as polyamides or coatings with specific surface properties.
• Chemical Biology Probes: Useful for the design and synthesis of activity-based probes or affinity labels targeting enzymes and receptors.

Basic Information

Product Name	5-(Aminosulphonyl)-2-Methoxybenzoyl Chloride
CAS No.	52542-44-6
Molecular Formula	C8H8ClNO4S
Molecular Weight	249.67 g/mol
Synonyms	2-Methoxy-5-sulfamoylbenzoyl chloride; 5-Sulfamoyl-2-methoxybenzoyl chloride; 2-Methoxy-5-sulfamoylbenzoic acid chloride; 5-Aminosulfonyl-2-methoxybenzoyl chloride; 5-Sulfamoyl-o-anisoyl chloride; Benzoic acid, 2-methoxy-5-sulfamoyl-, chloride; o-Anisic acid, 5-sulfamoyl-, chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(Aminosulphonyl)-2-Methoxybenzoyl Chloride is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.