Description

1-Carbethoxycyclopropyltriphenylphosphonium Tetrafluoroborate is a specialized organophosphorus salt widely utilized as a key reagent in advanced organic synthesis. Its primary value lies in its role as a stabilized ylide precursor for the synthesis of complex, strained-ring systems, particularly cyclopropane derivatives. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the construction of novel molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for constructing strained carbocyclic and heterocyclic scaffolds found in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides and insecticides that incorporate cyclopropane motifs for enhanced biological activity.
• Wittig Reaction Reagent: Serves as a specialized phosphonium ylide precursor for the stereoselective formation of alkenes fused to cyclopropane rings.
• Material Science: Employed in the synthesis of monomers and ligands for polymers and metal-organic frameworks (MOFs) with unique structural properties.
• Academic & Process Chemistry: A valuable tool for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Item	Details
Product Name	1-Carbethoxycyclopropyltriphenylphosphonium Tetrafluoroborate
CAS No.	52186-89-7
Molecular Formula	C24H26BF4O2P
Molecular Weight	464.24 g/mol
Synonyms	(1-Ethoxycarbonylcyclopropyl)triphenylphosphonium Tetrafluoroborate; Ethyl 1-(Triphenylphosphonio)cyclopropanecarboxylate Tetrafluoroborate; 1-(Ethoxycarbonyl)cyclopropyltriphenylphosphonium Tetrafluoroborate; Cyclopropanecarboxylic acid, 1-(triphenylphosphoranylidene)-, ethyl ester, inner salt, tetrafluoroborate(1-); Triphenyl(1-ethoxycarbonylcyclopropyl)phosphonium Tetrafluoroborate; Wittig Reagent for Cyclopropane Synthesis
EINECS	Contact for details

Quality Control

Our 1-Carbethoxycyclopropyltriphenylphosphonium Tetrafluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect reactivity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.