Description

1-Prop-2-Ynylpiperazine is a versatile heterocyclic building block featuring a piperazine core with a propargyl substituent. This compound is valued for its dual functionality, enabling its use as a key intermediate in advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research: Serves as a versatile synthon in medicinal chemistry for creating compound libraries via click chemistry (CuAAC) and other coupling reactions.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science: Potential monomer or cross-linking agent in the development of advanced polymers and functional materials.

Basic Information

Product Name	1-Prop-2-Ynylpiperazine
CAS No.	52070-67-4
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	1-Propargylpiperazine; N-Propargylpiperazine; 1-(Prop-2-yn-1-yl)piperazine; 2-Propyn-1-yl-piperazine; Propargylpiperazine; 52070-67-4; Piperazine, 1-(2-propynyl)-
EINECS	Contact for details

Quality Control

Our 1-Prop-2-Ynylpiperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.