Description

Ho-Peg3-Ch2Cooh is a heterobifunctional polyethylene glycol (PEG) derivative featuring a hydroxyl group and a carboxylic acid terminus, linked by a triethylene glycol spacer. This compound is a crucial building block in bioconjugation and pharmaceutical development, enabling the precise attachment of therapeutic molecules, imaging agents, or other functional moieties. It is primarily utilized by researchers and manufacturers in the fields of biopharmaceuticals, advanced drug delivery systems, and diagnostic probe development.

Application

• Bioconjugation Linker: Used to covalently link peptides, proteins, antibodies, or small molecule drugs to nanoparticles, surfaces, or other biomolecules.
• PEGylation Reagent: Serves as a functional PEG spacer to improve the solubility, stability, and pharmacokinetic profile of therapeutic agents.
• Polymer Chemistry: Acts as a monomer or macromonomer for synthesizing functionalized, biocompatible polymers and hydrogels.
• Diagnostic Probes: Facilitates the creation of labeled probes for imaging and diagnostic assays by conjugating targeting ligands with reporter molecules.
• Surface Modification: Employed to introduce hydrophilic, functional groups onto material surfaces for improved biocompatibility and specific binding.
• Cross-linking Agent: Utilized in the preparation of cross-linked networks for controlled release applications or scaffold fabrication.

Basic Information

Product Name	Ho-Peg3-Ch2Cooh
CAS No.	51951-05-4
Molecular Formula	C11H22O7
Molecular Weight	266.29 g/mol
Synonyms	3,6,9-Trioxaundecanedioic acid, 11-hydroxy-; 11-Hydroxy-3,6,9-trioxaundecanedioic acid; HO-PEG3-COOH; Hydroxy-PEG3-acid; 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]acetic acid; PEG3 acid alcohol; α-Hydro-ω-carboxy-triethylene glycol; Heterobifunctional PEG3 linker
EINECS	Contact for details

Quality Control

Our Ho-Peg3-Ch2Cooh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and pharmaceutical-grade applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Acid Value	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.