Description

Hydroxy-Peg2-Ch2Co2H is a high-purity, heterobifunctional polyethylene glycol (PEG) derivative featuring a terminal carboxylic acid and a hydroxyl group. This compound is a crucial building block in bioconjugation and pharmaceutical development, enabling the controlled linkage of molecules with different functionalities. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for creating PEGylated therapeutics, drug delivery systems, and functionalized polymers.

Application

• As a versatile linker in the synthesis of antibody-drug conjugates (ADCs) and other bioconjugates.
• For the PEGylation of peptides, proteins, and small molecule drugs to enhance solubility, stability, and circulation time.
• As a key intermediate in the development of functionalized hydrogels and biocompatible polymers for medical devices.
• In the preparation of surface modifiers and spacers for biosensors and diagnostic assays.
• For creating cross-linkers in material science to introduce hydrophilic PEG segments into polymer networks.
• As a reagent in organic synthesis to introduce carboxylic acid functionality via its PEG spacer.

Basic Information

Product Name	Hydroxy-Peg2-Ch2Co2H
CAS No.	51951-04-3
Molecular Formula	C7H14O6
Molecular Weight	194.18 g/mol
Synonyms	2-[2-(2-Hydroxyethoxy)ethoxy]acetic Acid; HO-PEG2-CH2COOH; Carboxy-PEG2-alcohol; 3,6-Dioxaoctanoic Acid, 8-hydroxy-; 8-Hydroxy-3,6-dioxaoctanoic Acid; 2,2'-Ethylenedioxybis(ethanol-1-carboxylic acid) (derivative); PEG2 Acid Alcohol; α-Hydro-ω-carboxypentaethylene glycol
EINECS	Contact for details

Quality Control

Our Hydroxy-Peg2-Ch2Co2H is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and biotech research. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.