Description

1,1-Cyclobutanedicarbonyl Dichloride (9Ci) is a high-purity, reactive organic intermediate of significant importance in advanced synthetic chemistry. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Peptide Mimetics & Conformationally Restricted Analogs: Used to introduce the rigid cyclobutane scaffold, which is valuable for creating peptide mimetics and analogs with enhanced metabolic stability and binding affinity.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides with unique modes of action.
• Polymer Chemistry: Employed as a monomer or cross-linking agent for producing specialty polymers with tailored thermal and mechanical properties.
• Material Science Research: Utilized in academic and industrial R&D for creating novel organic frameworks, ligands for catalysis, and advanced functional materials.
• Chemical Biology Probes: Acts as a reagent for modifying biomolecules or synthesizing chemical probes to study biological pathways and protein function.

Basic Information

Product Name	1,1-Cyclobutanedicarbonyl Dichloride (9Ci)
CAS No.	51816-01-4
Molecular Formula	C6H6Cl2O2
Molecular Weight	181.02 g/mol
Synonyms	Cyclobutane-1,1-dicarbonyl dichloride; 1,1-Cyclobutanedicarboxylic acid dichloride; Cyclobutanedicarbonyl dichloride; 1,1-Bis(chlorocarbonyl)cyclobutane; Cyclobutane-1,1-dicarboxylic acid chloride; 1,1-Cyclobutanedicarboxylic acid chloride; 1,1-Cyclobutanedicarboxylic dichloride; 1,1-Cyclobutanedicarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1,1-Cyclobutanedicarbonyl Dichloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.