Description

Calcium Dobesilate is a well-established pharmaceutical active ingredient and chemical intermediate. It is primarily valued for its vasoprotective and angioprotective properties, making it a key component in the formulation of medicines targeting vascular disorders. This compound is essential for manufacturers in the global pharmaceutical and fine chemical industries. Its consistent quality and reliable supply are critical for producing effective therapeutic treatments.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of oral medications and injectables for chronic venous insufficiency and diabetic retinopathy.
• Vascular Health Supplements: Used as a core component in dietary supplements aimed at supporting capillary integrity and microcirculation.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological and clinical research studies.
• Veterinary Pharmaceuticals: Incorporated into treatments for vascular-related conditions in animals.
• Cosmeceutical Formulations: Potential use in topical creams and serums designed to reduce dark circles and puffiness related to capillary fragility.

Basic Information

Product Name	Calcium Dobesilate
CAS No.	51579-78-3
Molecular Formula	C12H10CaO10S2
Molecular Weight	418.40 g/mol
Synonyms	Calcium Doxium; Calcium Dobesilate Monohydrate; Dobesilate Calcium; 2,5-Dihydroxybenzenesulfonic Acid Calcium Salt; Doxium; Doxi-OM; Doxium Calcium; Calcium 2,5-dihydroxybenzenesulfonate
EINECS	257-316-5

Quality Control

Our Calcium Dobesilate is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA), detailing identity, purity, and impurity profiles, is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (Calcium)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residue on Ignition	≤ 0.1%
Microbial Limits	Meets Ph. Eur. requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.