Description

(R)-2-Flurbiprofen CAS NO 51543-40-9 is the single enantiomer of the non-steroidal anti-inflammatory drug (NSAID) flurbiprofen, characterized by its specific (R)-configuration. This enantiopure compound is of significant value in pharmaceutical research and development, particularly for studying stereoselective drug metabolism and activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in chiral drug synthesis, pharmacokinetic studies, and the development of novel anti-inflammatory agents.

Application

• Chiral Pharmaceutical Intermediate: A key building block for the synthesis of enantiomerically pure NSAIDs and other active pharmaceutical ingredients (APIs).
• Pharmacological Research: Used as a reference standard and active agent in studies investigating the stereospecific pharmacokinetics, efficacy, and toxicity of flurbiprofen enantiomers.
• Biochemical Assay Development: Employed in the development and validation of analytical methods, such as chiral HPLC, for enantiomeric separation and purity analysis.
• Mechanism of Action Studies: A critical tool for elucidating the specific biological pathways and receptor interactions unique to the (R)-enantiomer.
• Academic Research: Serves as a standard compound in university and institutional labs for organic chemistry and medicinal chemistry education and projects.

Basic Information

Product Name	(R)-2-Flurbiprofen
CAS No.	51543-40-9
Molecular Formula	C15H13FO2
Molecular Weight	244.26 g/mol
Synonyms	(R)-Flurbiprofen; (2R)-2-(2-Fluorobiphenyl-4-yl)propanoic acid; (R)-2-Fluoro-α-methyl-4-biphenylacetic acid; Dexflurbiprofen (Note: Often refers to the (S)-enantiomer); (R)-(-)-Flurbiprofen; (R)-2-(4-Biphenylyl)propionic acid, 2'-fluoro-; (R)-FP; UNII-5V5IO2Q8F8
EINECS	257-235-3

Quality Control

Our (R)-2-Flurbiprofen is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC, to ensure high chemical and enantiomeric purity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and compliance with customer specifications. We support research and development with material suitable for use as a reference standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Melting Point	108°C - 112°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.