Description

Flurbiprofen is a potent non-steroidal anti-inflammatory drug (NSAID) belonging to the phenylalkanoic acid class. It is valued for its effective inhibition of cyclooxygenase (COX) enzymes, which are key mediators of inflammation and pain. This active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical industry developing analgesic and anti-inflammatory medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter (OTC) oral tablets and capsules for pain and inflammation management.
• Ophthalmic Solutions: Formulated in eye drops for the treatment of ocular inflammation following cataract surgery or other ophthalmic procedures.
• Topical Formulations: Incorporated into gels, creams, and patches for localized relief of musculoskeletal pain and inflammation.
• Veterinary Medicine: Used in veterinary pharmaceuticals for the management of pain and inflammation in animals.
• Research & Development: Serves as a critical reference standard and biochemical tool in pharmacological research studying COX inhibition and NSAID mechanisms.

Basic Information

Product Name	Flurbiprofen
CAS No.	51543-38-5
Molecular Formula	C15H13FO2
Molecular Weight	244.26 g/mol
Synonyms	(±)-2-Fluoro-α-methyl-4-biphenylacetic acid; (±)-Flurbiprofen; Ansaid; Froben; Cebutid; Flugalin; 2-(2-Fluorobiphenyl-4-yl)propanoic acid; 3-Fluoro-4-phenylhydratropic acid
EINECS	257-234-5

Quality Control

Our Flurbiprofen is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards, typically exceeding 99.0%. Testing includes identification, assay, and control of specified impurities and residual solvents in accordance with pharmacopeial guidelines. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Optical Rotation	-0.10° to +0.10° (c=1 in methanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.