Description

2-Chlorophenylacetyl Chloride is a versatile and highly reactive aromatic acid chloride derivative. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the 2-chlorophenylacetyl moiety. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of active pharmaceutical ingredients (APIs), advanced intermediates, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential central nervous system (CNS) agents and other therapeutic compounds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the chlorophenyl group contributes to biological activity.
• Peptide Mimetics & Modifications: Employed in medicinal chemistry for acylating amino groups to create peptide analogs and modified biomolecules.
• Dye & Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and colorants.
• Polymer Chemistry: Can be used as a monomer or modifying agent in the production of specialty polymers with specific functional properties.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for novel compound library synthesis and method development.

Basic Information

Item	Details
Product Name	2-Chlorophenylacetyl Chloride
CAS No.	51512-09-5
Molecular Formula	C8H6Cl2O
Molecular Weight	189.04 g/mol
Synonyms	2-Chlorobenzeneacetyl chloride; (2-Chlorophenyl)acetyl chloride; o-Chlorophenylacetyl chloride; 2-Chlorophenylethanoyl chloride; 2-Chloro-α-toluoyl chloride; NSC 403801; α-Chloro-o-toluoyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chlorophenylacetyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts violently with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent hydrolysis and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.