Description

[R-(R*,S*)]-β-Hydroxy-α-Methylphenethylammonium [R-(R*,R*)]-Hydrogen Tartrate CAS NO 51442-15-0 is a high-purity, stereochemically defined salt form of a key pharmaceutical intermediate. This compound is critical for ensuring the precise stereochemistry and stability required in advanced synthetic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Asymmetric Synthesis: Used in catalytic and stoichiometric asymmetric reactions to introduce specific stereocenters with high enantiomeric purity.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Process Chemistry R&D: Employed in route scouting and optimization studies for new chemical entities (NCEs) in both academic and industrial settings.
• Salt Formation Studies: Used in pre-formulation research to study the physicochemical properties of different salt forms of amine-containing APIs.

Basic Information

Item	Details
Product Name	[R-(R*,S*)]-β-Hydroxy-α-Methylphenethylammonium [R-(R*,R*)]-Hydrogen Tartrate
CAS No.	51442-15-0
Molecular Formula	C13H21NO6
Molecular Weight	287.31 g/mol
Synonyms	(-)-Pseudoephedrine Hydrogen Tartrate; (1S,2S)-2-Methylamino-1-phenylpropan-1-ol (2R,3R)-hydrogen tartrate; L-Pseudoephedrine Bitartrate; d-ψ-Ephedrine Hydrogen Tartrate; (1S,2S)-Pseudoephedrine (2R,3R)-Tartrate; α-(1-Methylaminoethyl)benzyl alcohol hydrogen tartrate; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our [R-(R*,S*)]-β-Hydroxy-α-Methylphenethylammonium [R-(R*,R*)]-Hydrogen Tartrate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and related substances is supplied with every order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.