Description

(10E,15Z)-9,12,13-Trihydroxyoctadeca-10,15-Dienoic Acid is a polyhydroxylated fatty acid derivative, also known as a trihydroxyoctadecadienoic acid. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a bioactive lipid mediator and potential precursor in specialized pro-resolving mediator (SPM) synthesis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on inflammation research, lipidomics, and the development of novel therapeutic agents.

Application

• Biochemical Research Standard: Used as a high-purity reference standard in lipidomics, metabolomics, and eicosanoid pathway analysis.
• Pharmaceutical R&D: Serves as a key intermediate or lead compound in the development of anti-inflammatory and pro-resolving therapeutic agents.
• Inflammation & Immunology Studies: Employed in cell culture and in-vivo models to study the mechanisms of inflammation resolution and immune modulation.
• Specialized Pro-Resolving Mediator (SPM) Synthesis: Acts as a biosynthetic precursor for the production of resolvins and other SPMs.
• Analytical Method Development: Used to develop and validate analytical methods (e.g., LC-MS/MS, HPLC) for the detection and quantification of oxylipins in biological samples.
• Cosmeceutical Research: Investigated for potential applications in advanced skincare formulations targeting inflammatory skin conditions.

Basic Information

Product Name	(10E,15Z)-9,12,13-Trihydroxyoctadeca-10,15-Dienoic Acid
CAS No.	51146-90-8
Molecular Formula	C₁₈H₃₀O₅
Molecular Weight	326.43 g/mol
Synonyms	9,12,13-Trihydroxy-10E,15Z-octadecadienoic acid; 9,12,13-TriHODE; (10E,15Z)-9,12,13-TriHOME; Trihydroxyoctadecadienoic acid; THODE; Fatty acid 18:3 (OH)₃; 9,12,13-Trihydroxyoctadeca-10,15-dienoic acid; (10E,15Z)-9,12,13-Trihydroxyoctadecadienoic acid
EINECS	Contact for details

Quality Control

Our (10E,15Z)-9,12,13-Trihydroxyoctadeca-10,15-Dienoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. Due to its hygroscopic and light-sensitive nature, allow the sealed container to reach room temperature before opening to prevent moisture condensation. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.