Description

(R)-(-)-Ibuprofen CAS NO 51146-57-7 is the single enantiomer form of the widely used non-steroidal anti-inflammatory drug (NSAID) ibuprofen, specifically the (R)-enantiomer. This high-purity chiral intermediate is critical for pharmaceutical research and development focused on enantiomerically pure active pharmaceutical ingredients (APIs). It is primarily required by advanced pharmaceutical manufacturers and research institutions engaged in developing novel therapeutics with improved efficacy and reduced side-effect profiles, as well as for use as a reference standard in analytical laboratories.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of enantiomerically pure APIs and prodrugs.
• Pharmacological Research: Used in studies to investigate the distinct metabolic pathways, pharmacokinetics, and biological activity of the (R)-enantiomer.
• Analytical Reference Standard: Employed as a high-purity standard for method development, validation, and quality control in chiral HPLC and other analytical techniques.
• Asymmetric Synthesis Studies: Utilized in academic and industrial research focused on chiral resolution techniques and stereoselective synthesis.
• Development of Novel NSAIDs: Acts as a starting material for the research and development of next-generation anti-inflammatory agents with targeted mechanisms.

Basic Information

Product Name	(R)-(-)-Ibuprofen
CAS No.	51146-57-7
Molecular Formula	C13H18O2
Molecular Weight	206.28 g/mol
Synonyms	(R)-Ibuprofen; (R)-(-)-Ibuprofen; Dexibuprofen Impurity; (2R)-2-[4-(2-Methylpropyl)phenyl]propanoic Acid; (R)-α-Methyl-4-(2-methylpropyl)benzeneacetic Acid; (R)-p-Isobutylhydratropic Acid; Dexibuprofen Related Compound A; (R)-Form of Ibuprofen
EINECS	Contact for details

Quality Control

Our (R)-(-)-Ibuprofen is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay, to ensure it meets stringent specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and related substances is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.